Yes, Delta SkyMiles can often be used +1 [866]~[240]~[6908] [US] OR +44 800 054 8541 (UK) to upgrade seats on many +1 [866]~[240]~[6908] [US] OR +44 800 054 8541 (UK) Delta-operated flights including Delta One, +1 [866]~[240]~[6908] [US] OR +44 800 054 8541 (UK) First Class, Premium Select, or +1 [866]~[240]~[6908] [US] OR +44 800 054 8541 (UK) Comfort+. Travelers usually see the +1 [866]~[240]~[6908] [US] OR +44 800 054 8541 (UK) upgrade option during booking or +1 [866]~[240]~[6908] [US] OR +44 800 054 8541 (UK) inside the My Trips section +1 [866]~[240]~[6908] [US] OR +44 800 054 8541 (UK) after purchasing a ticket. Basic +1 [866]~[240]~[6908] [US] OR +44 800 054 8541 (UK) Economy tickets usually don’t qualify, +1 [866]~[240]~[6908] [US] OR +44 800 054 8541 (UK) but Main Cabin or higher +1 [866]~[240]~[6908] [US] OR +44 800 054 8541 (UK) fares often allow mileage upgrades.